Status:
COMPLETED
Melatonin Production Delay in Preterm Infants
Lead Sponsor:
Tel Aviv University
Conditions:
Melatonin Production
Eligibility:
All Genders
9-12 years
Brief Summary
Objective: Melatonin production is known to be delayed in preterm-born infants up to 6 months of age. This might be related to exposure of preterm infants to continuous lighting in the NICU during a c...
Detailed Description
Unlike other organs which show catch up in preterm infants after one year of life, the pineal gland shows persistent delay in melatonin production. This field of research has been neglected lately alt...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- The investigators included healthy mothers with singleton pregnancies and documented prenatal care who were admitted before term (28-34) weeks gestation to the hospital's delivery room with early uterine contractions and entering stage 1 of an anticipated spontaneous vaginal delivery or term infants born at 38-42 weeks of gestation.
- Exclusion criteria:
- Mothers who showed signs of fetal distress during labor, or required Cesarean (C)c-section, or had fetuses withand estimated fetal weights \< 10th percentile for gestational age and children diagnosed with
- Genetic anomalies, congenital heart malformations, gastrointestinal disturbances and central nervous system dysfunction
- Age \< 9 months, Age \> 9 months month at onset of study
- Considered medically unstable
Exclusion
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2008
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT00775723
Start Date
January 1 2008
End Date
May 1 2008
Last Update
November 3 2008
Active Locations (1)
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1
Rambam Medical Center
Haifa, Israel