Status:
UNKNOWN
Anti-Inflammatory and Anti-Platelet Effect of Clopidogrel and Aspirin vs Aspirin Alone in Symptomatic Polyvascular Disease and in Patients With Multiple Recurrent Cardiovascular Events
Lead Sponsor:
Catholic University of the Sacred Heart
Conditions:
Polyvascular Disease
Cardiovascular Disease
Eligibility:
All Genders
40-75 years
Phase:
PHASE3
Brief Summary
This is a monocentric, randomized, opened study to assess the anti-inflammatory and anti-platelet effect of Clopidogrel and aspirin versus aspirin or clopidogrel alone in patients with symptomatic pol...
Eligibility Criteria
Inclusion
- Patients with symptomatic polyvascular disease or recurrent cardiovascular events. In particular patients with established stable coronary artery disease associated with peripheral disease or cerebrovascular disease and patients with more than two acute cardiovascular events.
Exclusion
- chronic treatment with anticoagulant drugs and the use of other antiplatelet therapy;
- intolerance/allergy to Aspirin or to Clopidogrel
- platelet counts outside the range of 125-450 10\^9/l
- inflammatory or infectious disease
- malignancies or immunologic or hematological disorders.
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2010
Estimated Enrollment :
213 Patients enrolled
Trial Details
Trial ID
NCT00775762
Start Date
November 1 2008
End Date
December 1 2010
Last Update
October 20 2008
Active Locations (1)
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1
Catholic University of the Sacred Heart, Department of Cardiovascular Medicine
Rome, Italy, 00135