Status:

COMPLETED

Increasing Ferulic Acid Bioavailability in Bran

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Healthy Males

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

The aim of the present study is to investigate the effect of pretreatment of bran on improving the bioavailability of ferulic acid in wholegrain breads containing bran. As secondary endpoints we will ...

Detailed Description

Rationale: Whole grain consumption has been associated with a lower risk of developing metabolic syndrome, cardiovascular disease, type 2 diabetes and some type of cancers. Whole grain is a good sourc...

Eligibility Criteria

Inclusion

  • Healthy males
  • Age \> 18
  • 20 \< BMI \< 30

Exclusion

  • Use of any medication
  • Smoking
  • Consumption of 3 or more glasses of alcoholic drinks per day
  • Donation of more than 500 ml blood (\<6 months prior to the start of the study)
  • Vegetarian lifestyle (because the standardised meal contains meat)
  • Allergic reaction to some component in cereals e.g. celiac subjects

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2009

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT00777543

Start Date

November 1 2008

End Date

December 1 2009

Last Update

August 9 2018

Active Locations (1)

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University of Maastricht

Maastricht, Netherlands, 6200 MD