Status:

COMPLETED

Caloric Restriction, Exercise, and Glucoregulation in Humans

Lead Sponsor:

St. Louis University

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Diabetes

Eligibility:

All Genders

45-65 years

Phase:

NA

Brief Summary

Weight loss induced by caloric restriction alone (CR) and by exercise alone (EX) result in similar effects on blood glucose and insulin. The purpose of this study is to assess the hypothesis that weig...

Detailed Description

Participants are randomized into caloric restriction, exercise, and caloric restriction plus exercise weight loss groups. Measurements of blood glucose and insulin, oral glucose tolerance, and matched...

Eligibility Criteria

Inclusion

  • females postmenopausal
  • no diabetes, cardiovascular disease, cancer
  • no orthopedic problems
  • not currently exercising
  • BMI between 25 and 29.9
  • nonsmokers

Exclusion

  • current regular exercisers
  • premenopausal women
  • cardiovascular disease, lung disease, cancer, diabetes

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

69 Patients enrolled

Trial Details

Trial ID

NCT00777621

Start Date

April 1 2008

End Date

March 1 2015

Last Update

February 12 2016

Active Locations (1)

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Saint Louis University

St Louis, Missouri, United States, 63104