Status:
COMPLETED
Uncomplicated Nausea and Vomiting in the Emergency Department
Lead Sponsor:
WellSpan Health
Conditions:
Nausea
Vomiting
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Nausea and vomiting is a common complaint in the emergency department. Treatment is important for many reasons. In addition to patient comfort, there are adverse effects secondary to vomiting such as ...
Detailed Description
This study will compare Ondansetron 4 mg vs 2 mg vs Metoclopramide 10 mg to look for efficacy in nausea and vomiting treatment for patients in the ED with many different causes. We will also look for ...
Eligibility Criteria
Inclusion
- 18 years or older with nausea and at least 1 episode vomiting in the last 12 hours presenting to the York Hospital Emergency Department
Exclusion
- Patients known to have hypersensitivity to the drugs ondansetron or metoclopramide
- gastrointestinal hemorrhage, mechanical obstruction or perforation
- patients with pheochromocytoma
- seizure disorder
- patients receiving other drugs which are likely to cause extrapyramidal reactions such as butapherones and phenothiazines
- patients experiencing hyperemesis gravidum
- patients unable to understand the informed consent (intoxicated, Spanish speaking)
- prior antiemetics within 12 hours
- inability to perform visual analog scale
- renal dialysis
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
137 Patients enrolled
Trial Details
Trial ID
NCT00778011
Start Date
November 1 2005
End Date
December 1 2006
Last Update
June 28 2012
Active Locations (1)
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1
York Hospital
York, Pennsylvania, United States, 17405