Status:
UNKNOWN
The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics
Lead Sponsor:
University of Western Ontario, Canada
Conditions:
Osteoarthritis, Knee
Eligibility:
All Genders
60-80 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine the impact of a regular course of treatment with Hyaluronic acid (HA) injections on gait in knee osteoarthritis (OA) patients. Three consecutive HA injections...
Detailed Description
Knee osteoarthritis (OA) is a severely debilitating disease associated with stiffness and pain in the knee joint, and with a loss of function. Hyaluronic acid (HA) injections are incorporated into non...
Eligibility Criteria
Inclusion
- 60 - 80 years old.
- Mild to moderate knee osteoarthritis:
- Clinical diagnosis (symptoms).
- Radiographic diagnosis (Kellgren-Lawrence grade I - III).
- Must provide provide informed consent and knowledge of all possible benefits and possible adverse events.
- Available for duration of the study.
- Not taking any other knee osteoarthritis medications during the study.
Exclusion
- Non - OA arthritides.
- Hip, ankle, or foot OA.
- End stage OA.
- Lower back/extremity pathology.
- Previous surgery on knee affected by OA (except arthroscopy within the past 12 - 18 months).
- Neurological/Cardiovascular gait impairment.
- Pregnant.
- Cognitively impaired.
- Not available for duration of study.
- Taking other knee OA medications at time of study.
- Gastro-intestinal disturbance.
- Avian allergy or any other contraindication to intra-articular injections with Hyaluronic acid.
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00778076
Start Date
July 1 2008
End Date
May 1 2009
Last Update
April 1 2009
Active Locations (1)
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1
St. Joseph's Health Care, Parkwood Hospital, Aging Rehabilitation and Geriatric Care research center
London, Ontario, Canada, N6C 5J1