Status:
COMPLETED
Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.
Lead Sponsor:
Oregon Health and Science University
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Oregon Clinical and Translational Research Institute
Conditions:
Post-Traumatic Stress Disorders
Eligibility:
All Genders
25-65 years
Phase:
NA
Brief Summary
The purpose of this study is to find out how meditation influences certain systems in the body: nervous system, hormonal system, and respiratory system. Another purpose is to see how meditation may he...
Detailed Description
This study requires nine visits to the clinic: one screening visit, one baseline visit, six training sessions, and one endpoint visit. There will be approximately 100 people enrolled in this study who...
Eligibility Criteria
Inclusion
- Combat veteran (defined by a score of ≥7 on the Combat exposure scale)
- Chronic PTSD diagnosis
- Age range (25-65 years)
- Both genders
- Good general medical health
- Stable dose of medications for concurrent stable medical conditions for at least 4 weeks prior to start of the study.
- Willing and able to provide informed consent.
Exclusion
- Significant chronic medical illness including:
- current cancer treatment,
- unstable angina,
- recent myocardial infarction,
- current or past history of stroke,
- transient ischemic attack,
- congestive heart failure,
- chronic renal or hepatic failure,
- hypothyroidism
- Psychiatric or behavioral illness including:
- schizophrenia,
- schizoaffective disorder,
- bipolar disorder,
- psychotic disorder (not including transient dissociative states or flashbacks associated with PTSD re-experiencing symptoms),
- any DSM-IV cognitive disorder,
- current delirium,
- psychiatric instability or situational life crises, including evidence of being actively suicidal or homicidal, or any behavior which poses an immediate danger to the patient or others.
- Substance dependence disorder within 3 months of the study or
- current substance use other than alcohol (no more than 2 drinks/day by self-report)
- Sexual assault as primary PTSD event/s.
- Planning to move from the area in the next year.
- Prior or current meditation practice.
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT00778960
Start Date
January 1 2009
End Date
May 1 2014
Last Update
July 13 2015
Active Locations (1)
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1
Oregon Health and Science University
Portland, Oregon, United States, 97239