Status:
UNKNOWN
Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
Lead Sponsor:
Odense University Hospital
Collaborating Sponsors:
LEO Pharma
University of Southern Denmark
Conditions:
Dermatitis, Contact
Dermatitis, Occupational
Eligibility:
All Genders
18-45 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the efficacy of glycerol ointment, triamcinolone acetonide ointment, clobetasol ointment and tacrolimus ointment on irritated skin in a cumulative skin irritati...
Detailed Description
Irritant contact dermatitis (ICD) is a frequent cause of hand eczema and occupational skin disease. One way to study ICD is to expose healthy volunteer skin to chemicals and evaluate the skin response...
Eligibility Criteria
Inclusion
- caucasian
- normal skin on both volar forearms
- oral and written informed consent
Exclusion
- pregnant, lactating women
- no safe anticonceptive method used
- intake of systemic immunosuppressants (e.g. prednisolone)
- endocrine, immune, or liver disorders
- known allergy towards drugs applied to the skin
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2008
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00779792
Start Date
September 1 2008
End Date
November 1 2008
Last Update
October 24 2008
Active Locations (1)
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1
Department of Dermatology, Odense University Hospital
Odense, Denmark, 5000