Status:
COMPLETED
Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Gambro Industries, MEYZIEU, France
URC-CIC Paris Descartes Necker Cochin
Conditions:
Cardiac Arrest
Sudden Cardiac Death
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Rationale: Despite spontaneous cardiac activity recovery, a shock occurs in more than half of patients after resuscitation for cardiac arrest. This acute circulatory insufficiency presents similar cha...
Detailed Description
HDHP (plasma epuration of inflammatory mediators) will be used in addition to the current clinical practice. The experimental arm will be treated by HDHP device. The high permeability membrane SepteX...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Comatous patients admitted to the ICU for a sudden cardiac death apparently related to heart disease and requiring catecholamine infusion to treat a shock
- Cardiac arrest in front of witnesses
- Written informed consent obtained from the family or by emergency procedure
- Exclusion criteria
- Age under 18 years
- Response to verbal commands (Glasgow score \>7)
- Terminal illness present before the cardiac arrest
- Acquired or innate immune deficit
- Anticoagulation not recommended or high hemorrhagic risk
- pregnancy
- weight \> 100 kg
- without social security
- another clinical trial ongoing
- cardiac arrest from non cardiac etiology
Exclusion
Key Trial Info
Start Date :
November 2 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 2 2016
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00780299
Start Date
November 2 2008
End Date
January 2 2016
Last Update
September 8 2025
Active Locations (1)
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1
Medical intensive care unit of Cochin-St Vincent de Paul university Hospital
Paris, France, 75679