Status:

TERMINATED

Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder

Lead Sponsor:

IWK Health Centre

Conditions:

Overactive Bladder

Eligibility:

FEMALE

Phase:

NA

Brief Summary

The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic ther...

Detailed Description

Urinary symptoms such as frequency, urgency, nocturia, and incontinence occur in many women. Overactive bladder (OAB) accounts for forty to seventy percent of urinary incontinence. These symptoms can ...

Eligibility Criteria

Inclusion

  • Women with OAB symptoms including urgency, frequency (voids ≥8/day), and urge incontinence
  • Women who consume \> one cup (250ml) caffeinated beverage per day
  • Women who score $ 6 on the QUID Questionnaire for urgency symptoms

Exclusion

  • Women currently receiving treatment for OAB symptoms
  • Women with narrow angle Glaucoma
  • Women taking anticholinergics or loop diuretics
  • Women with an untreated urinary tract infection. After resolution of the UTI, and if all other eligibility criteria are met, the woman can be a candidate for inclusion in the study.
  • Women with a diagnosis of painful bladder syndrome or other abnormal urinary tract lesions
  • Women scoring \>4 on the QUID Questionnaire for stress symptoms
  • Women with de novo symptoms following surgery
  • Women with major pelvic prolapse

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2013

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT00780832

Start Date

May 1 2008

End Date

April 1 2013

Last Update

February 24 2016

Active Locations (1)

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IWK Health Centre

Halifax, Nova Scotia, Canada, B3K 6R8