Status:
COMPLETED
Comparison of Phenprocoumon and Acetylsalicylic Acid (ASA)
Lead Sponsor:
RWTH Aachen University
Conditions:
Valvular Calcification
Coronary Calcification
Eligibility:
All Genders
50-90 years
Brief Summary
In this open, prospective, non-randomised, parallel group, unicentric pilot-study will be compared the progress of valvular and coronary calcification with regard to the therapy with either acetyl-sal...
Detailed Description
Patients will be allocated to two groups with either 1. anticoagulation with phenprocoumon (needed for at least 1 year) 2. therapy with ASA Both treatment groups should include to 50% patients with ...
Eligibility Criteria
Inclusion
- 60 patients with new onset of anticoagulation therapy with phenprocoumon for the expectant duration of at least one year
- BMI 19-27 kg/qm
- Mental ability and capacity to understand and follow the instructions of the investigator
- Written informed consent
Exclusion
- Patients not fulfilling the inclusion criteria or with:
- renal failure grade IV or V
- acute cardial or pulmonary decompensation
- women of childbearing age, pregnant or breastfeeding women
- psychiatric diseases
- life expectancy \< 1 year
- acute lifethreatening situations
- participation in other studies
- persons in dependency from the sponsor or working with the sponsor
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
157 Patients enrolled
Trial Details
Trial ID
NCT00782743
Start Date
February 1 2008
End Date
August 1 2015
Last Update
September 23 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Medicine, Division of Cardiology, Pulmonology and Vascular Medicine
Aachen, North Rhine-Westphalia, Germany, 52074