Status:

COMPLETED

Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Conditions:

Procedural Sedation

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

The use of procedural sedation and analgesia (PSA) to accomplish painful procedures in the emergency department (ED) has become a standard of practice over the last decade. Substantial variance exists...

Eligibility Criteria

Inclusion

  • Patients with orthopedic injuries requiring painful manipulation (i.e. reduction of fracture or dislocation, drainage of abscess, suture of extensive laceration)
  • Age between18-65 years
  • American Society of Anesthesiologists (ASA) score of 1 or 2
  • Systolic blood pressure higher than 90 mmHg and lower than 160 mmHg before initiating sedation
  • Willingness and ability to provide an informed consent
  • No known hypersensitivity to either medication
  • No evidence of intoxication
  • No recent heavy meal.

Exclusion

  • Pregnant women and patients who do not meet the above criteria will be excluded.

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00784498

Start Date

November 1 2008

End Date

September 1 2009

Last Update

August 3 2010

Active Locations (1)

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Tel Aviv Sourasky Medical Center

Tel Aviv, Israel