Status:
UNKNOWN
Advanced MRI in Blast-related TBI
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
Landstuhl Regional Medical Center
U.S. Army Medical Research and Development Command
Conditions:
Traumatic Brain Injury
Eligibility:
All Genders
18+ years
Brief Summary
Thousands of soldiers, marines, and other military personnel have had injuries to the brain due the wars in Iraq and Afghanistan. In addition, 1.5 million civilians per year in the United States have ...
Detailed Description
Background: In traumatic brain injury, axonal damage is a major pathophysiological process and may be a primary cause of adverse neurological outcomes. However, traumatic axonal injury and its effects...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Clinical diagnosis of blast-related TBI of any severity, as made by LRMC staff, based on clinical history, examination, and/or standard clinical imaging (CT, conventional MRI).
- Acute injury or injuries, defined as first occurring 0-90 days prior to enrollment.
- Ability to lie still in a supine position for the duration of the scan sessions, e.g. no severe claustrophobia or limiting pain from other injuries.
- No known metallic implants or metallic foreign objects.
- Ability to provide informed consent.
- Not known to be HIV positive
- Not known to be pregnant
- No previous major traumatic brain injury
- No contraindication to MRI for medical reasons such as arrhythmias.
Exclusion
Key Trial Info
Start Date :
November 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2016
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00785304
Start Date
November 1 2008
End Date
July 1 2016
Last Update
December 10 2014
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Washington University
St Louis, Missouri, United States, 63110
2
Landstuhl Regional Medical Center
Landstuhl, Kirchberg, Germany, 66849