Status:
COMPLETED
Study Using Esomeprazole as a Diagnostic Test for GERD in Patients With NCCP
Lead Sponsor:
National University Hospital, Singapore
Conditions:
Gastroesophageal Reflux Disease
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Gastroesophageal reflux disease (GERD), with its cardinal symptom, heartburn, is the most common disorder of the esophagus in the West. Comparatively, GERD is less common in Singapore but its frequenc...
Eligibility Criteria
Inclusion
- patients with recurrent chest pain of more than three months duration with either (1) normal or non-obstructive coronary arteries (\<50% luminal diameter narrowing), (2) normal dobutamine stress echocardiography or (3) a negative exercise electrocardiogram and a cardiologist's evaluation that symptoms are not cardiac in origin.
Exclusion
- Patients will be excluded if they are \< 18 or \> 70 years old, are pregnant, have a medical contraindication for esomeprazole therapy, have already been empirically treated with an antireflux regimen, report a history of peptic ulcer disease or gastrointestinal surgery, or are unwilling or unable to provide informed consent. In addition, patients who are unable to fully complete all stages of the study will be excluded.
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00786695
Start Date
May 1 2006
End Date
December 1 2009
Last Update
March 4 2011
Active Locations (1)
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1
National University Hospital
Singapore, Singapore, 119074