Status:
COMPLETED
Measurement of Glucose/Glycogen Metabolism in Humans Using Magnetic Resonance at 4 or 7 Tesla
Lead Sponsor:
University of Minnesota
Conditions:
Type 1 Diabetes
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
The long-range goal of this project is to determine the effects of diabetes and the hypoglycemic consequences of intensive therapy on in vivo brain glucose metabolism in humans. We will measure brain ...
Detailed Description
On the morning before the study subjects will report to the Clinical Research Center and will be asked to stay at the Clinical Research Center for up to 72 hours. You will be asked not to eat anything...
Eligibility Criteria
Inclusion
- Age 18-65
- Healthy control
- Must be able to provide informed consent
- Type 1 diabetes with hypoglycemia unawareness with hemoglobin A1c \< 7.5%
- Poorly controlled diabetics with hemoglobin A1c \> 7.5%
- Subjects with hypoglycemia unawareness must report an inability to recognize at least some blood glucose values \<58 mg/dL during the 3 months prior to the study.
Exclusion
- Over 300 pounds
- Claustrophobic
- History of ischemic heart disease, arrhythmia, of seizure disorder
- Pregnant
- On medications known to alter blood flow or carbohydrate metabolism
- Have internally located pieces of metal
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00786825
Start Date
December 1 2004
End Date
December 1 2017
Last Update
December 18 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Minnesota
Minneapolis, Minnesota, United States, 55414