Status:
COMPLETED
The Effect of Glucose-Insulin-Potassium Infusion in Patients Undergoing Cardiac Surgery
Lead Sponsor:
Christoph Ellenberger
Conditions:
Aortic Stenosis
Coronary Heart Disease
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the cardioprotective effects of a short term infusion of glucose-insulin-potassium (GIK) during heart surgery.
Detailed Description
Cardiac surgery with cardiopulmonary bypass and ischemic cardiac arrest is associated with a wide spectrum of perioperative myocardial ischemic-reperfusion injuries resulting in significant cardiac mo...
Eligibility Criteria
Inclusion
- Severe aortic stenosis
- Coronary artery disease associated with poor left ventricular function
- Parsonnet score \>7
Exclusion
- Dementia or inability to understand the study protocol
- Off-pump and emergent cardiac surgery
- Poorly controlled diabetes mellitus
- Severe renal insufficiency
- Abnormal liver function Child-Plugh - C
- Body Mass Index \< 18 and \> 35
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00788242
Start Date
January 1 2009
End Date
December 1 2013
Last Update
November 23 2016
Active Locations (2)
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1
Geneva University Hospital
Geneva, Canton of Geneva, Switzerland, 1211
2
Cardiocentro
Lugano, Canton Ticino, Switzerland, 6900