Status:
UNKNOWN
Cortical Excitability in Patients With Severe Brain Injury
Lead Sponsor:
University of Aarhus
Conditions:
Severe Traumatic Brain Injury
Subarachnoid Hemorrhage
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of the study is to evaluate the cortical excitability in the severe brain injured patients. We hypothesize that: 1. There is a continuous decrease in intracortical inhibition from healthy sub...
Detailed Description
Design: Prospective controlled non-randomized study. Materials and methods: 30 patients with severe brain injury and 15 healthy volunteers will be included in this study. The study design is illustra...
Eligibility Criteria
Inclusion
- severe brain injury (Glasgow Coma Scale score (GCS) less than 8 on admission to the acute hospital);
- stable vital functions;
- age over 18 years old;
- informed content from patient/relatives/legal guardian.
Exclusion
- other neurological diseases than brain injury;
- pregnancy;
- TMS contraindications (epilepsy, metallic implantants: pacemaker or medicine pump, ferromagnetic or electronically operated stapedial implants, haemostatic clips, metallic splinters in the orbit).
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2009
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00788723
Start Date
July 1 2008
End Date
May 1 2009
Last Update
November 11 2008
Active Locations (1)
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1
Hammel Neurorehabilitation and Research Centre
Hammel, Denmark, 8450