Status:

COMPLETED

Determine The Percentage Of Depressed Outpatients Who Do Not Effectively Metabolize Extended-release Venlafaxine HCl

Lead Sponsor:

Wyeth is now a wholly owned subsidiary of Pfizer

Conditions:

Depression

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This is a study to determine the percentage of patients with depression who are treated with extended-release venlafaxine HCl (U.S. marketed brand Effexor XR®) who are Poor Metabolizers (based on the ...

Eligibility Criteria

Inclusion

  • Men and women subjects aged 18 years or older.
  • Current outpatient treatment with extended-release venlafaxine HCl (U.S. marketed brand Effexor XR®), within the US Food and Drug Administration (FDA)-approved dosage range for depression (37.5 mg/day to 225 mg/day), for 8 weeks or less.
  • Ability to have a blood draw within 4 to 12 hours of the most recent dose of Effexor XR®.

Exclusion

  • Determination by the investigator that a blood draw is contraindicated.
  • Participation in an investigational study within the past 30 days where the study medication is not known.
  • Previous treatment with Effexor XR® or extended-release venlafaxine HCl (generic) in the 6 months prior to current treatment regimen.
  • Treatment with DVS SR within the last 30 days.

Key Trial Info

Start Date :

October 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

971 Patients enrolled

Trial Details

Trial ID

NCT00788944

Start Date

October 1 2008

End Date

July 1 2009

Last Update

January 7 2011

Active Locations (52)

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Page 1 of 13 (52 locations)

1

Pfizer Investigational Site

Birmingham, Alabama, United States, 35216

2

Pfizer Investigational Site

Tuscon, Arizona, United States, 85710

3

Pfizer Investigational Site

Little Rock, Arkansas, United States, 72223

4

Pfizer Investigational Site

National City, California, United States, 91950