Status:
UNKNOWN
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Hearing Loss
Eligibility:
All Genders
Phase:
PHASE2
PHASE3
Brief Summary
Disequilibrium between acid and base in the inner ear was suggested to be an important factor leading to hearing impairment associated with SLC26A4 mutations. For acid-base homeostasis in the inner ea...
Detailed Description
Hereditary hearing loss is the most common inherited sensory defect, affecting about 1 per 1000 children. With the advances in molecular genetics, the nature of hereditary hearing loss has started to ...
Eligibility Criteria
Inclusion
- Patients with homozygous or heterozygous SLC26A4 mutations
- Patients with acute hearing loss
Exclusion
- Patients who do not fulfill both of the above criteria
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2009
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00789061
Start Date
August 1 2006
End Date
July 1 2009
Last Update
November 11 2008
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100