Status:
UNKNOWN
Analysis of Cortical Excitability in Neuropathic Pain
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Neuropathic Pain
Cortical Excitability
Eligibility:
All Genders
20-65 years
Brief Summary
The purpose of this study is to determine whether patients with neuropathic pain has abnormal excitability in somatosensory cortex and abnormal sensory-motor connections.
Detailed Description
There are several brain areas responsible for neuropathic pain reported in functional image studies, including primary sensory cortex, insula, and anterior cingulate gyrus. However, it is few informat...
Eligibility Criteria
Inclusion
- Healthy volunteers
- patients with pain resulted from dysfunction of peripheral or central nervous system
- the disorders of peripheral nerves are diagnosed by nerve conduction study, quantitative sensory test, quantification of skin innervation or contact heat evoked potentials
- lesion of central nervous system should be confirmed by neuroimage.
Exclusion
- previous history of epilepsy, seizure disorders or major head injury
- previous brain surgery or intracranial metalic implant
- implanted devices as cardiac pacemaker
- pregnant subjects
- patient with severe cardiac or pulmonary disease who potentially cannot tolerate stress
Key Trial Info
Start Date :
October 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2011
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00789347
Start Date
October 1 2008
End Date
October 1 2011
Last Update
April 2 2010
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100