Probiotics for Girls With Recurring Urinary Tract Infections

Status:

WITHDRAWN

Probiotics for Girls With Recurring Urinary Tract Infections

Lead Sponsor:

Baylor College of Medicine

Conditions:

Recurrent Urinary Tract Infection

Eligibility:

FEMALE

3-17 years

Phase:

PHASE2

Brief Summary

Probiotics are dietary supplements containing potentially beneficial bacterial strains such as Lactobacillus. The safety of oral administration of probiotics has been demonstrated in hundreds of studi...

Eligibility Criteria

Inclusion

Girls age 1 through age 17 years of age
Must have had at least 3 symptomatic UTI, uncomplicated or complicated, in the year preceding study inclusion or already using any form of prophylaxis to prevent recurrences of UTI
Must have had at least 3 symptomatic urinary tract infections in the year before the start of the prophylaxis.

Exclusion

Breastfeeding
Pregnancy
Prior adverse reaction to sulfa drugs or sulfamethoxazole/trimethoprim
Known immunosuppression i.e., transplant recipients or children with congenital immunodeficiencies
Poorly controlled diabetes
Untreated HIV infection
Use of high dose corticosteroids for autoimmune diseases or post-organ transplantation. Inhaled corticosteroids or oral steroids for asthma are allowed.
Malnutrition
Patients with a history of sulfamethoxazole/trimethoprim-resistant UTI will be excluded from the study
Patients with renal insufficiency, liver insufficiency, or cardiopulmonary disease requiring medication will be excluded from the study
Patients with known anemia will be excluded from the study
Patients taking medications that may interact with sulfamethoxazole/trimethoprim will be excluded from the study
Patients taking other probiotics will be excluded from the study
Patients already taking prophylactic antibiotics will be excluded from the study

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00789464

Last Update

August 18 2020

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