Status:
UNKNOWN
Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery
Lead Sponsor:
University of Dublin, Trinity College
Collaborating Sponsors:
Abbott
Conditions:
Esophageal Cancer
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
This study aims to examine whether providing tube feeding with a formula enriched with omega-3 fats is better than traditional standard tube feeding in terms of preserving nutritional status, improvin...
Detailed Description
Title A double blinded randomized controlled trial to investigate the effects of an enteral nutritional supplement enriched with Eicosapentaenoic acid on long term nutritional status post operatively ...
Eligibility Criteria
Inclusion
- Adult (male \& female) patients \>18 years with resectable esophageal cancer
Exclusion
- Patients with metastatic disease,
- Non-operable cases,
- Patients requiring chemotherapy/radiotherapy early following surgery,
- Patients with known immunological disorder,
- Emergency esophagectomy cases,
- Patients with cardiac, liver or renal failure,
- Active small intestinal disease eg Crohns disease,
- Allergy to any of the ingredients,
- Uncontrollable Diabetes,
- Use of medications known to affect eicosanoid metabolism in two weeks prior to trial,
- Use of fish oil/n-3 fatty acids,
- Drug Abuse,
- Unable to take preparation for 5 days preoperatively,
- Pregnant women,
- Cessation of enteral feeding for longer than 3 consecutive days post operatively for medical/surgical reasons (e.g. Chyle leaks).
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2010
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00790140
Start Date
July 1 2005
End Date
July 1 2010
Last Update
November 13 2008
Active Locations (1)
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1
St. James's Hospital,
Dublin, Ireland, 8