Status:
TERMINATED
Effects of Humidity (During CPAP Treatment) on Mucociliary Clearance in Patients With Obstructive Sleep Apnea
Lead Sponsor:
Fisher and Paykel Healthcare
Conditions:
Obstructive Sleep Apnea
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
That the level of humidification delivered to patients during CPAP treatment will alter the subjects mucociliary clearance rate and related mucus properties.
Eligibility Criteria
Inclusion
- Moderate to severe obstructive sleep apnea - Apnea Hypopnea Index (AHI) \> 15
- 75% of events during the diagnostic study must be obstructive
Exclusion
- Currently using CPAP treatment OR have used it in the past 4 weeks
- Intolerance of CPAP and/or CPAP mask in the past or during the titration night
- Mouth breather (unable to breath through mouth for the study period)
- \< 18years old
- Nasal CPAP intolerance determined in the PSG-CPAP titration study
- Serious nasal issues
- Acute upper airway disease
- Smoker
- COPD
- Congestive heart failure
- Neuromuscular disease
- Stroke
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 24 2009
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT00790166
Start Date
October 1 2008
End Date
June 24 2009
Last Update
April 27 2018
Active Locations (1)
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1
Faculty of Medicine: Pulmonology: University of Sao Paulo Hospital
São Paulo, Brazil