Status:
TERMINATED
Proportional Assist Ventilation vs Pressure Support Ventilation
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
Medtronic - MITG
Conditions:
Respiration, Artificial
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In this study, we want to compare two different kinds of artificial ventilation to see if one encourages faster weaning from breathing support and if one provides better sleep quality. These artificia...
Eligibility Criteria
Inclusion
- Tracheotomized or endotracheally intubated and mechanically ventilated patients transferred or scheduled to be transferred to the RACU.
- Age 18 years or older.
Exclusion
- Patients who are weaned from ventilatory support within the first 72 hours of transfer to the RACU. Even though these patients had been randomized, they will be excluded. They will be considered in the intention to treat analysis but the final outcome analysis will be performed after their exclusion.
- High spinal cord injury
- Immunosuppressed patients receiving chemotherapy or radiation therapy (\< 2 months after chemotherapy or radiation therapy).
- Neuromuscular/ neurological disease of a progressive nature resulting in chronic ventilator dependence.
- High risk of mortality within 3 months (severe neurological damage and cancer patients in terminal stages of the disease).
- Patients unable to trigger the ventilator for any reason.
- Any patient who is not considered a candidate for weaning from ventilatory support
- Patients consented for another interventional study.
- Patients requiring more than 30 days to wean once randomized will be excluded. They will be considered in the intention to treat analysis but the final outcome analysis will be performed after their exclusion.
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00790725
Start Date
November 1 2008
End Date
May 1 2010
Last Update
April 25 2012
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114