Status:

UNKNOWN

Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology

Lead Sponsor:

Central Hospital, Nancy, France

Conditions:

Severe Sepsis

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

The objective of this pilot study is to estimate a procedure where the biological samples routinely obtained at the site of suspected infection could be guided by the early realization of a TEP with F...

Detailed Description

Severe sepsis constitutes the leading cause of mortality in ICU, in particular because a microbial documentation is lacking in about half of the cases. Tomography by emission of positons, which uses ...

Eligibility Criteria

Inclusion

  • Patient hospitalized with severe sepsis
  • Absence of infected site clearly identified after 48 hours of a conventional diagnosis assessment or suspicion of one or more additional sites
  • Indication of scanner X with injection
  • Informed consent obtained

Exclusion

  • Age over 80
  • Immunocompromised status
  • Surgical intervention within the previous month
  • Hemodynamic instability (defined by the use of more than 0.5µg/kg/min vasopressors)
  • Severe hypoxia (defined by a PaO2/FiO2 ratio lower than 150)
  • Pregnancy
  • Patient already included in another protocol
  • Anaphylaxis to Flucis

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2010

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00791310

Start Date

November 1 2008

End Date

October 1 2010

Last Update

December 31 2010

Active Locations (1)

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1

CHU; Central Hospital

Nancy, France, 54000