Status:

COMPLETED

Prenatal Corticosteroids and Antioxidants in Preterm Infants

Lead Sponsor:

Fundacion Para La Investigacion Hospital La Fe

Collaborating Sponsors:

University of Valencia

Carlos III Health Institute

Conditions:

Oxidative Stress

Eligibility:

All Genders

Brief Summary

Premature infants are highly susceptible to oxidative stress because of the immaturity of their antioxidant defense system. The use of prenatal glucocorticosteroids administered to the mother improves...

Detailed Description

This is an observational study recruiting extremely low gestational age neonates (\<28 weeks gestation) whose mothers received or not full scheduled prenatal glucocorticosteroids. Healthy term newly b...

Eligibility Criteria

Inclusion

  • Gestational age \<28 weeks
  • Registered used or not of prenatal glucocorticosteroids by the mother

Exclusion

  • Use of pro-or-antioxidant drugs by the mother during gestation
  • Major congenital malformations
  • Prenatal inflammation (E.G.:chorioamnionitis)
  • Chromosomopathies
  • Uncertainty about gestational age

Key Trial Info

Start Date :

January 1 2003

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2005

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT00791687

Start Date

January 1 2003

End Date

January 1 2005

Last Update

November 14 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Division of Neonatology; University Hospital La Fe

Valencia, Valencia, Spain, 46009