Status:
UNKNOWN
Social Skills Training in Refractory Schizophrenia
Lead Sponsor:
University of Sao Paulo
Conditions:
Schizophrenia and Disorders With Psychotic Features
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
Objective Primary: To evaluate the efficacy of social skills training in reducing negative symptoms in patients with refractory schizophrenia, in comparison with control (befriending group). Seconda...
Detailed Description
In schizophrenia positive symptoms can be improved with an antipsychotic treatment. However there is a subgroup of patients who have a predominance of persistent negative symptoms that do not respond ...
Eligibility Criteria
Inclusion
- Diagnosis of schizophrenia can´t not be over 10 years old.
- Age between 18 and 55 years old.
- A minimum of 16 in negative subscale of PANSS.
- A score 4 in at least 3 of the following symptoms:
- blunted affect
- social withdrawal
- rapport
- passive social withdrawal
- lack of spontaneity
- motor retardation
- active social avoidance
- Stable disease, in use of clozapine, without recent hospitalization.
Exclusion
- Comorbid substance use.
- Axis I comorbidity.
- History of head trauma or neurological disease.
- Clinical problems which can affect central nervous system.
- Mental retardation.
- Patients treated with other antipsychotic than clozapine.
- Patients who underwent other psychosocial treatments.
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2011
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT00791882
Start Date
August 1 2009
End Date
August 1 2011
Last Update
November 30 2009
Active Locations (1)
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1
Instituto de Psiquiatria do HCFMUSP
São Paulo, São Paulo, Brazil, 05403000