Status:
UNKNOWN
Specific Inspiratory Muscle Training (SIMT)in the Patients With Ventilatory Dependence
Lead Sponsor:
Saikaew Chuachan
Collaborating Sponsors:
Khon Kaen University
Conditions:
Ventilatory Defect
Eligibility:
All Genders
30+ years
Phase:
NA
Brief Summary
Prolong mechanical ventilation cause to respiratory muscle weakness and high risk to weaning failure,the investigators hypothesize that 1. Specific inspiratory muscle training (SIMT) using threshold ...
Detailed Description
Prolonged mechanical ventilation cause detrimental effects on lung function and high risk of lung complications and standard weaning protocols are not successful in a number of patients. The strength ...
Eligibility Criteria
Inclusion
- Patient who have been mechanically ventilated \> 72 hours and start to weaning from medical order or ventilator dependent patients who have failed to wean prior to study.
- Normal arterial blood gas (PaCO2 \< 50mmHg, PaO2 \> 60 mmHg on FiO2 \<0.5 or SaO2 \> 90%, PH 7.35-7.45).
- Cardiovascular stability (HR ≤ 140 beats/min, systolic BP 90-140 mmHg and diastolic BP 60-90 mmHg, with no or minimal vasopressors)
- Good consciousness, cooperation and can sit in an upright position \> 30 minutes
Exclusion
- Persistent homodynamic instability.
- Severe breathlessness at rest when spontaneous breathing.
- Coronary heart disease with angina.
- Life threatening arrhythmia (VF, VT).
- Sedation Ramsay scale \> 2
- Severity of disease APACHE II score \> 29
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2015
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00792441
Start Date
January 1 2007
End Date
December 1 2015
Last Update
April 3 2015
Active Locations (1)
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1
Respiratory Intensive Care Unit (RICU),Srinagarind Hospital
Khon Kaen, Changwat Khon Kaen, Thailand, 40002