Status:
COMPLETED
Perioperative Parathormone Measurement and Sodium Bicarbonate Infusion Test After Total Thyroidectomy
Lead Sponsor:
Aristotle University Of Thessaloniki
Collaborating Sponsors:
AHEPA University Hospital
Conditions:
Hypoparathyroidism
Eligibility:
All Genders
18+ years
Brief Summary
In the study will be included patients that have undergone total thyroidectomy and do not display obvious clinical or laboratory hypoparathyroidism. On the third postoperative day and before the patie...
Detailed Description
Each patient will undergo a thorough preoperative examination for the presence of abnormalities in calcium, phosphate or magnesium metabolism as a consequence of a primary or a secondary disease. Blo...
Eligibility Criteria
Inclusion
- Inclusion criteria for the patient group
- Patient is over 18 years old
- Patient scheduled for total thyroidectomy
- Patient signs and dates a written informed consent form (ICF) and indicates an understanding of the study procedures
- Exclusion criteria the patient group:
- Primary hyperparathyroidism
- Primary hypoparathyroidism
- Diabetes mellitus
- Chronic Renal Failure
- Hypoalbuminemia
- Systematic Diseases (e.g., infections, neoplasmas)
- Thyroid or parathyroid cancer
- Osteoporosis
- Drugs that influence calcium metabolism (vitamin D analogues, oral calcium supplements, biphosphonates, teriparatide, thiazide diuretics)
- Osteomalacia
- Neck irradiation
- Inclusion criteria for the control group
- Participant is over 18 years old
- Participant signs and dates a written informed consent form (ICF) and indicates an understanding of the study procedures
- Exclusion criteria of the control group:
- 1\. All the above mentioned, in addition to prior thyroid surgery.
Exclusion
Key Trial Info
Start Date :
March 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2009
Estimated Enrollment :
127 Patients enrolled
Trial Details
Trial ID
NCT00793689
Start Date
March 1 2008
End Date
October 1 2009
Last Update
October 16 2009
Active Locations (1)
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1
AHEPA University Hospital
Thessaloniki, Greece, 54636