Status:

TERMINATED

A Pilot Study Comparing the Programmed Delay Between the Atrial and Ventricle Interval

Lead Sponsor:

University of Minnesota

Collaborating Sponsors:

Minnesota Medical Foundation

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

The idea of this study is to compare different ways of setting up a pacemaker, using blood tests to give us information about how well it's working. We hope to learn if we can use this approach to fig...

Detailed Description

There are different kinds of pacemakers and different ways they can be set up to try to make the heart beat regularly. A normal heart has four chambers; these four chambers pump in a co-ordinated way ...

Eligibility Criteria

Inclusion

  • Diagnosis of chronic heart failure
  • patients on stable pharmacologic therapy for at least 3 months
  • EF\< 35%
  • age \>18 years
  • NYHA functional class III or IV
  • eligible for either CRT pacer or CRT defibrillator for heart failure
  • Ischemic or non-ischemic cardiomyopathy
  • patients that are able to tolerate VDD mode with a lower rate of 40bpm programming

Exclusion

  • systolic blood pressure \<70mmHg
  • Likely to receive a left ventricular assist device or cardiac transplant within 6 months of implant procedure
  • patients who have previously received a CRT device
  • documented atrial fibrillation
  • complete heart block

Key Trial Info

Start Date :

June 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2010

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00794183

Start Date

June 1 2004

End Date

November 1 2010

Last Update

June 26 2012

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55455