Status:

TERMINATED

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety

Lead Sponsor:

Pfizer

Conditions:

Pulmonary Arterial Hypertension

Pulmonary Hypertension

Eligibility:

All Genders

16-80 years

Phase:

PHASE3

Brief Summary

As sitaxsentan is the agent most highly selective for ETA (Endothelin Type A (receptor)), and does not significantly impact sildenafil pharmacokinetics the combination of most promise for pulmonary ar...

Eligibility Criteria

Inclusion

  • Previously enrolled in B1321001 for at least 4 weeks.
  • Previously enrolled in B1321003, discontinued from the study.
  • Completed the B1321003 study as planned.

Exclusion

  • Treated with an investigational drug (other than sitaxsentan or sildenafil in either B1321001 or B1321003) or device that has not received regulatory approval within the 30 days prior to Baseline/Day 1 or during the study.

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2011

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT00796510

Start Date

July 1 2010

End Date

January 1 2011

Last Update

October 25 2018

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Pfizer Investigational Site

Fountain Valley, California, United States, 92708

2

Pfizer Investigational Site

Cluj-Napoca, Romania, 400 001

3

Pfizer Investigational Site

Kyiv, Ukraine