Status:

COMPLETED

Using Functional MRI to Evaluate Cognitive Behavioral Therapy Treatment Response in Adults With Chronic Pain

Lead Sponsor:

University of Vermont

Collaborating Sponsors:

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Conditions:

Chronic Pain

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

Chronic pain is a condition in which pain continues for 1 month or more beyond the usual recovery period for an injury or illness or persists for months or years due to a chronic condition. A commonly...

Detailed Description

Many recent studies have suggested that there is an overlap between pain and emotion-related neurophysiological processes. Several modern pain theories also advocate that pain should be considered as ...

Eligibility Criteria

Inclusion

  • At least 6 months of musculoskeletal non-neuropathic pain confined to lumbar or thoracic back
  • Meets study threshold for severity of typical pain of 4 or more on a 10-point scale adapted from the McGill Pain Questionnaire
  • Has ongoing standard pain management from a physician
  • Agrees to participate in this research study

Exclusion

  • Malignancy
  • Reflex sympathetic dystrophy and/or naturopathic pain
  • Opioid medication use
  • Substance use disorder
  • Neurological disorder, such as epilepsy, stroke, or other medical condition that could confound or interfere with the current study
  • Major depression or/and dysthymia
  • Post traumatic stress disorder or panic disorder
  • Left-handedness
  • Pregnancy
  • History of illicit drug use (cocaine, cannabis, heroin) that can result in altered cognition
  • Exceeding the weight limit on the MRI scanner
  • Suffering from claustrophobia
  • Any of the following: cardiac pacemakers, auto defibrillators, neural stimulators, aneurysm clips, metallic prostheses, cochlear implants, any implanted devices (pumps, infusion devices, stents), permanent eye make-up, intrauterine devices, shrapnel injuries

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00796536

Start Date

June 1 2009

End Date

July 1 2011

Last Update

February 18 2013

Active Locations (1)

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MindBody Medicine Clinic

Burlington, Vermont, United States, 05401