Status:

TERMINATED

Dantrolene for Treatment of Hyperthermia in Subarachnoidal Hemorrhage (SAH)

Lead Sponsor:

Medical University of Vienna

Conditions:

Hyperthermia

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

PHASE3

Brief Summary

Dantrolene is used to prevent hyperthermia in intensive care patients suffering from subarachnoidal hemorrhage.

Detailed Description

Background: Fever episodes occur in more than 50% of patients admitted to the ICU for subarachnoidal hemorrhage, central nervous system infection, seizure control, hemorrhagic stroke, and closed head...

Eligibility Criteria

Inclusion

  • neurosurgical patients after subarachnoidal hemorrhage
  • breathing spontaneously or being ventilator dependant
  • sustained fever (≥38ºC for more than an hour) without an identifiable infectious cause.

Exclusion

  • infection
  • pregnancy
  • arrhythmia
  • muscular dystrophia
  • acute liver disease

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2011

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT00796900

Start Date

May 1 2008

End Date

March 1 2011

Last Update

May 12 2011

Active Locations (1)

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1

Medical University Vienna

Vienna, Austria, 1090