Status:
COMPLETED
The Body's Response to Food Intake in Older Adults
Lead Sponsor:
Purdue University
Conditions:
Elderly
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
We propose to critically evaluate the effects of energy-yielding fluids and solids on acute appetite variables, daily food intake, and specific endocrine and metabolic response to food in the elderly....
Eligibility Criteria
Inclusion
- Age range: 60 years and older
- Body mass index between 20-29 kg/m2
- Weight stable (\< 2 kg weight change within last 6 months)
- Non-smoking
- Constant habitual activity patterns within last 3 months
- Clinically normal blood profiles (specifically, normal liver and kidney function; normal complete blood count (non-anemic); fasting blood glucose \<110 mg/dl)
- Not taking medications known to influence appetite or metabolism
- Non-diabetic
- Resistive exercise training (≤2 times a week) based on reported physical activity levels (questionnaire)
- Active fitness level (≤3, 30-minute aerobic exercise sessions/week)
- Confirmation of acceptability of eating the study test foods (solids and fluids)
Exclusion
- Age: \<60 years
- Body mass index: outside of the 20-29 kg/m2 range
- Gained or lost \> 4.5 kg within the last 6 months
- Smoker (currently or within the last year)
- Intermittently been involved in a diet and/or exercise program within the last 3 months
- Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
- Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
- Abnormal heart function (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD
- Clinically diagnosed as diabetic
- Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
- Perform ≥ 2, 30-minute aerobic exercise sessions/week (currently or within the last 3 months) based on physical activity levels (questionnaire)
- Study foods are found to be unacceptable for consumption by the subject
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2008
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00798408
Start Date
February 1 2006
End Date
January 1 2008
Last Update
September 24 2013
Active Locations (1)
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1
Purdue University
West Lafayette, Indiana, United States, 47907