Status:
WITHDRAWN
Amantadine and Temporal Discrimination in Patients With Traumatic Brain Injury (TBI)
Lead Sponsor:
Wake Forest University Health Sciences
Conditions:
Traumatic Brain Injury
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
The study will explore the neurocognitive effect of four weeks of treatment with amantadine versus placebo in patients with traumatic brain injury using the Interval Bisection Timing Task. Approximate...
Eligibility Criteria
Inclusion
- Age 18 to 55 inclusive. History of post-MVA close head TBI. Female subjects must use an acceptable method of contraception during entire study. Acceptable methods of contraception are: history of surgical sterility, postmenopausal status, hormonal contraceptives, or accepted barrier devices (i.e., male/female condom, diaphragm, cervical cap, intrauterine device).
Exclusion
- Current or past history of major psychiatric disorder (schizophrenia, bipolar disorder, major depressive disorder)
- Substance use disorder
- Current or past history of serious chronic medical condition (pulmonary (lung), cardiovascular (heart), hepato-renal (liver-kidney) disease, diabetes)
- Seizures
- Smoking one or more packs of cigarettes per day
- If you are pregnant or breastfeeding, or plan to become pregnant during the study
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00800514
Start Date
January 1 2009
End Date
November 1 2010
Last Update
April 27 2022
Active Locations (1)
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1
CHS-Behavioral Health Research
Charlotte, North Carolina, United States, 28211