Status:

UNKNOWN

Pelvic Fractures and Radiation Therapy for Cervical Cancer

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Cervical Cancer

Endometrial Cancer

Eligibility:

FEMALE

Brief Summary

The goal of this study is to estimate how often pelvic fractures occur in women treated with radiation therapy for either newly diagnosed or recurrent cervical, endometrial, or vaginal cancer. The stu...

Detailed Description

If you agree to take part in this study, the following tests and procedures will be performed before radiation therapy: * You will have a bone mineral density test. A bone mineral density test measur...

Eligibility Criteria

Inclusion

  • Patients with histologically confirmed primary or recurrent cervical , endometrial or vaginal cancer. All stages, grades and histologic subtypes will be eligible except neuroendocrine.
  • Patients treated with definitive radiation therapy. Patients receiving extended field radiation or brachytherapy in addition to pelvic radiation are eligible. Patients treated with surgery, chemotherapy and/or hormonal therapy in addition to radiation therapy are also eligible.
  • Patients must sign an approved informed consent document.

Exclusion

  • Patients undergoing palliative intent radiation therapy for advanced disease.
  • Patients who received prior radiation to the pelvis.
  • Patients with an existing pelvic fracture within the proposed radiation field.
  • Patients unwilling or unable to provide informed consent for the study.
  • Patients with bone metastases.
  • Neuroendocrine features present.
  • Patients weighing more than 300 lbs are excluded as they cannot be adequately studied in axial skeleton with current bone mineral density software.

Key Trial Info

Start Date :

November 5 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 30 2020

Estimated Enrollment :

239 Patients enrolled

Trial Details

Trial ID

NCT00800644

Start Date

November 5 2008

End Date

November 30 2020

Last Update

January 13 2020

Active Locations (1)

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1

University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030