Status:

COMPLETED

CrossBoss and Stingray Catheter and Entera Guidewire Chronic Total Occlusion (CTO) Study

Lead Sponsor:

Boston Scientific Corporation

Collaborating Sponsors:

BridgePoint Medical

Conditions:

Coronary Artery Disease

Coronary Artery Chronic Total Occlusion

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

This study is to determine if the BridgePoint Medical System (CrossBoss Catheter, Stingray Catheter, Entera Guidewire) can facilitate safe and effective placement of a guidewire in the true lumen of c...

Eligibility Criteria

Inclusion

  • Suitable for coronary intervention
  • de novo or restenotic CTO at least 3 months old, in proximal or mid coronary artery segment, 3.0-5.0 mm in diameter
  • Mild/moderate proximal vessel tortuosity
  • Mild/moderate lesion angulation
  • Mild/moderate calcification
  • Satisfactory distal vessel visualization
  • Mild/moderate side branch interference
  • 19 years old
  • BMI\<40
  • LVEF\>20%
  • Signed informed consent

Exclusion

  • Extensive dissection from guidewire manipulation
  • SVG or in-stent CTO
  • Aorto-ostial CTO
  • Unable to take aspirin, Clopidogrel, or Ticlopidine
  • Thrombus/vessel filling defects
  • Severe cerebrovascular disease/stroke within 1 month
  • Intervention within 2 weeks
  • Renal insufficiency
  • GI bleeding
  • Active infection
  • Life expectancy \<2 years
  • Significant anemia
  • Uncontrolled hypertension
  • Severe electrolyte imbalance
  • Anaphylaxis to contrast
  • NYHA class IV
  • Unstable angina requiring intervention
  • MI within 2 weeks
  • Uncontrolled diabetes
  • Participating in another protocol
  • Unwilling/unable to comply with protocol
  • Angina/ischemia caused by target vessel

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2009

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT00801710

Start Date

September 1 2008

End Date

September 1 2009

Last Update

January 26 2021

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Main Taunus Hospital

Bad Soden, Germany

2

Klinikum Darmstadt

Darmstadt, Germany

3

CardioVascular Center Frankfurt, St. Katharinen Hospital

Frankfurt, Germany

4

Universitäres Herz- und Gefässzentrum Hamburg

Hamburg, Germany