Status:

COMPLETED

Hybrid SA RGP Center/S-H Skirt Daily Wear 90 Day Multicenter Study

Lead Sponsor:

SynergEyes, Inc.

Conditions:

Corneal Disease

Hypersensitivity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of the study is to demonstrate that the SynergEyes SA Hybrid Contact Lens clinical performance is substantially equivalent to that of the SynergEyes A Hybrid Lens when studied: * within t...

Detailed Description

The objective of the study is to compare the SynergEyes SA Hybrid Contact Lens (Test) to the SynergEyes A Hybrid Contact lens (Control) when used in a daily wear regimen on non-diseased eyes for the c...

Eligibility Criteria

Inclusion

  • Prior to being considered eligible to participate in this study, each subject MUST:
  • Be at least 18 years of age as of the date of evaluation.
  • Have
  • read the Informed Consent,
  • been given an explanation of the Informed Consent,
  • indicated an understanding of the Informed Consent and
  • signed the Informed Consent Form.
  • Be willing and able to adhere to the instructions set forth in this protocol and able to keep all specified appointments.
  • Be a current contact lens wearer.
  • Possess wearable and visually functional eyeglasses.
  • Be in good general health, based on his/her knowledge.
  • Require spectacle lens powers between plano and -6.00 diopters sphere with no more than -2.50 diopters of spectacle refractive astigmatism and be willing to wear lenses in both eyes.
  • Have manifest refraction visual acuity equal to or better than 20/25 in each eye.

Exclusion

  • Subjects may not be enrolled into the study if ANY of the following apply:
  • Subject is wearing lenses in a monovision modality and is unwilling to be fit with distance lenses in both eyes. NOTE: Subjects may NOT wear monovision lenses at any time during the study as it will interfere with the distance visual acuity measurement.
  • Subject exhibits poor personal hygiene.
  • Subject is currently or within 30 days prior to this study has been an active participant in another clinical study.
  • Subject is currently pregnant (to the best of the subject's knowledge), is planning a pregnancy within the next 3 months or is lactating.
  • Subject is a member, relative or household member of the office staff, including the investigator(s).
  • Subject has a known sensitivity to ingredients used in contact lens care products or over-the-counter lubricants and artificial tears.
  • Subject has undergone refractive surgery or is currently receiving or has previously received orthokeratology treatment.
  • Subject is aphakic or pseudophakic.
  • Subject has ocular or systemic disease such as, but not limited to: anterior uveitis or iritis (past or present), glaucoma, Sjögren's syndrome lupus erythematosus, scleroderma, keratoconus or type II diabetes.
  • Use of ocular medications for any reason or systemic medications which might interfere with contact lens wear.
  • A known history of corneal hypoesthesia (reduced corneal sensitivity).
  • Slit lamp findings that would contraindicate contact lens wear, including but not limited to:
  • History of corneal ulcer, corneal infiltrates or fungal infections
  • Corneal scars within the visual axis
  • Pterygium
  • Dry eye symptoms with decrease tear levels and punctate staining ≥ Grade 2
  • Neovascularization or ghost vessels \> 1.5 mm in from the limbus
  • Seborrhoeic eczema, seborrhoeic conjunctivitis
  • History of papillary conjunctivitis that has interfered with lens wear or a current condition of Grade 2 (Mild) or greater
  • Clinically significant (Grade 3 or 4) anterior segment abnormalities or any infection of the eye, lids, or associated structures.
  • TO BE ELIGIBLE TO BE RANDOMIZED FOR STUDY PRODUCT TRIAL A SUBJECT MUST HAVE ALL OF THE INCLUSION CRITERIA AND NONE OF THE EXCLUSION CRITERIA PRESENT.
  • TO BE ELIGIBLE FOR LENS DISPENSING, THE SUBJECT'S STUDY DEVICE CONTACT LENS VISUAL ACUITY MUST BE EQUAL TO OR BETTER THAN 20/30 IN EACH EYE

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT00804505

Start Date

June 1 2008

End Date

December 1 2008

Last Update

December 23 2009

Active Locations (8)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 2 (8 locations)

1

Carmel Mountain Vision Care

San Diego, California, United States, 92129

2

Silicon Valley Eye Physicians

Sunnyvale, California, United States, 94087

3

Casazza Optometric Group

Andover, Massachusetts, United States, 01810

4

Vision Care Associates

East Lansing, Michigan, United States, 48823