Status:

COMPLETED

Urinary Kidney Injury Molecule-1 (KIM-1) Excretion As Biomarker for Injury in Kidney Transplant Recipients

Lead Sponsor:

Northwell Health

Collaborating Sponsors:

Astellas Pharma US, Inc.

Conditions:

Kidney Transplant Dysfunction

Eligibility:

All Genders

3-18 years

Brief Summary

The purpose of this study is to determine if measuring the level of a protein called Kidney Injury Molecule-1 (KIM-1) in the urine will help healthcare providers detect any problems with the transplan...

Detailed Description

SPECIFIC AIMS: 1. To investigate the role of urinary Kim-1 excretion as a marker of delayed graft function, acute kidney allograft rejection and/or virus-induced allograft nephropathy and/or calcineu...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Children and adults from the age of 3 years who are eligible transplant candidates listed for deceased donor kidney or who are scheduled for a living related or unrelated donor kidney transplant at Mount Sinai Hospital will be eligible for inclusion in this project. Patients will be recruited from the population awaiting kidney transplant treated at the Schneider Children's Hospital and Mount Sinai Hospital.

Exclusion

    Key Trial Info

    Start Date :

    October 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT00805571

    Start Date

    October 1 2008

    Last Update

    March 12 2010

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Schneider Children's Hospital

    New Hyde Park, New York, United States, 11040