Status:

COMPLETED

Evaluation of the Analgesy With Emla and/or Nitrous Oxide in Pediatric Patients for Lumbar Puncture

Lead Sponsor:

Federal University of Minas Gerais

Conditions:

Leukemia

Non Hodgkin Lymphoma

Eligibility:

All Genders

4-14 years

Phase:

PHASE4

Brief Summary

In this randomised controlled study the investigators intended to compare the analgesic effects of EMLA and\\or nitrous oxide in children submitted to lumbar puncture.

Detailed Description

It is a randomized controlled clinical trial, double blinded, with the purpose to compare the use of EMLA - local anesthetic (lidocaine and prilocaine), and or nitrous oxide at 50% in oxygen (Livopan®...

Eligibility Criteria

Inclusion

  • Age between four and 14 years;
  • Not present cognitive disabilities;
  • Necessity to perform the clinical procedure;
  • Accordance in participating in the study.

Exclusion

  • Continuity skin lesion in the procedure site;
  • Metahemoglobinemia;
  • Neuromuscular disability;
  • Presence of pneumothorax, emphysema, intra-abdominal infection, cranioencephalic traumatism, otitis media, sinusitis and intracranial hypertension;
  • Vitamin B12 known deficits;
  • Urgency for the procedure;
  • Disagreement in participating of the project;
  • Patients in use of Dapsone.

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT00808171

Start Date

February 1 2009

End Date

August 1 2011

Last Update

July 29 2014

Active Locations (1)

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Department of Pediatrics - Hematology section - Clinical Hospital of Minas Gerais

Belo Horizonte, Minas Gerais, Brazil