Status:
COMPLETED
Efficacy of N-Acetylcysteine in Prevention of Post-Catheterization Contrast-Induced Nephropathy in Diabetic Patients With Chronic Kidney Disease
Lead Sponsor:
Tehran University of Medical Sciences
Conditions:
Radiocontrast-Induced Nephropathy
Chronic Kidney Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
* Contrast-induced nephropathy (CIN) is the third most common cause of hospital acquired acute kidney injury, accounting for 10% of all cases. * The pathophysiology of CIN is unclear. Possible mechani...
Detailed Description
* Contrast-induced nephropathy (CIN) is the third most common cause of hospital acquired acute kidney injury, accounting for 10% of all cases. Nevertheless, use of radiocontrast media has been associa...
Eligibility Criteria
Inclusion
- Patients who have all of the following criteria:
- Aged older than 18 years old
- A history of diabetes mellitus for at least one year
- chronic kidney disease, defined as serum creatinine concentration \>=1.5mg/dL for men and \>=1.4mg/dL for women.
Exclusion
- Acute coronary syndrome requiring primary or rescue coronary intervention within less than 12h
- Cardiogenic shock
- Current peritoneal or hemo-dialysis
- A known allergy to NAC
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2006
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00808795
Start Date
April 1 2006
End Date
October 1 2006
Last Update
December 16 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tehran Heart center
Tehran, Tehran Province, Iran, 1411713138