Status:

COMPLETED

Vitamin D AND Glucose Handling Evaluated by Glucose Clamp

Lead Sponsor:

University Hospital of North Norway

Collaborating Sponsors:

Norwegian Council on Cardiovascular diseases

Conditions:

Insulin Sensitivity

Intraocular Pressure

Eligibility:

All Genders

30-75 years

Phase:

PHASE2

Brief Summary

In this study the investigators want to compare glucose handling (insulin secretion and insulin sensitivity) in 100 persons with low and 50 persons with normal-high levels of vitamin D, using a hyperg...

Eligibility Criteria

Inclusion

  • generally: Subjects are recruited from the 6th Tromsø Study
  • cases: serum 25-hydroxyvitamin D-levels below the 10 percentile; low levels confirmed with new serum analyses.
  • controls: serum 25-hydroxyvitamin D levels 80-95 percentile, normal-high levels confirmed with new serum analyses.

Exclusion

  • diabetes
  • myocardial infarction or apoplexia
  • active cancer during last 5 years
  • history of kidney stone
  • pregnancy or premenopausal without safe anticonception
  • primary hyperparathyroidism
  • systolic blood pressure \>175 or diastolic blood pressure \>105

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT00809744

Start Date

November 1 2008

End Date

December 1 2010

Last Update

November 3 2011

Active Locations (1)

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1

University Hospital of North Norway

Tromsø, Norway, 9037