Status:
COMPLETED
Tocolysis for Preterm Labor
Lead Sponsor:
University of Mississippi Medical Center
Conditions:
Preterm Labor
Eligibility:
FEMALE
16-45 years
Phase:
NA
Brief Summary
Preterm birth is the most common and costly complication in obstetrics. It complicates up to 11% of all pregnancies and it is responsible for 70% of sick babies. The ideal way to stop preterm labor wh...
Detailed Description
Preterm labor is the most common complication of pregnancy and one of the most catastrophic occurring in 10-12% of all pregnancies and accounting for up to 80% of the neonatal morbidity1. In addition,...
Eligibility Criteria
Inclusion
- Pregnancies with intact membranes in confirmed preterm labor;
- 20 - 32 weeks' gestation;
- Cervical dilatation 0 - 3cm versus 4 - 6cm;
- No conditions contraindicating continued pregnancy (severe IUGR, chorioamnionitis, non-reassuring fetal tracing - physician judgement); AND
- Able and willing to consent to the study protocol.
Exclusion
- Failure to meet admission criteria;
- Known serious fetal malformations;
- Severe maternal/obstetric disease affecting the mother or fetus (severe cardiac disease, placental abruption/previa, severe diabetes, severe preeclampsia, etc. - physician judgment);
- Allergic to magnesium, antiprostaglandin or calcium channel antagonist;
- Refusal or inability to consent to the study
Key Trial Info
Start Date :
June 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
301 Patients enrolled
Trial Details
Trial ID
NCT00811057
Start Date
June 1 2004
End Date
June 1 2010
Last Update
April 4 2013
Active Locations (1)
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1
The Winfred L. Wiser Hospital for Women and Infants at the University of Mississippi Medical Center
Jackson, Mississippi, United States, 39216