Status:

COMPLETED

Pediatric Bipolar Depression

Lead Sponsor:

AstraZeneca

Conditions:

Bipolar Depression

Eligibility:

All Genders

10-17 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine if quetiapine fumarate extended-release (quetiapine XR or SEROQUEL® XR) 150 to 300 mg/day taken by itself is effective and safe in treating children or adoles...

Eligibility Criteria

Inclusion

  • Provision of informed consent by one or both parents or legal guardian and written assent by the patients before any study procedures are performed.
  • The patient must have a documented clinical diagnosis for bipolar I or bipolar II disorder, and including current episode depressed.
  • Patients are required to be in outpatient status at the enrollment and randomization visits and believed likely to remain an outpatient for the duration of the study.
  • Patients must be able to swallow the study medication tablets.

Exclusion

  • The patient must not have been diagnosed with Tourette's Disorder, Obsessive-Compulsive Disorder, acute Post-traumatic Stress Disorder, Panic Disorder, Autistic Disorder and/or Asperger's Disorder.
  • Patient can not have a history of non-response to an adequate treatment to more than 2 antidepressants during the current episode.
  • The patient must not have received electroconvulsive therapy (ECT) within 30 days before participating in the study.
  • Patients who in your doctors judgement pose a current suicidal or homicidal risk.

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2010

Estimated Enrollment :

193 Patients enrolled

Trial Details

Trial ID

NCT00811473

Start Date

January 1 2009

End Date

November 1 2010

Last Update

July 15 2014

Active Locations (48)

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Page 1 of 12 (48 locations)

1

Research Site

Dothan, Alabama, United States

2

Research Site

Scottsdale, Arizona, United States

3

Research Site

Little Rock, Arkansas, United States

4

Research Site

Escondido, California, United States