Status:
TERMINATED
Neurovascular Coupling in Patients With Open Angle Glaucoma
Lead Sponsor:
Medical University of Vienna
Conditions:
Glaucoma
Eligibility:
All Genders
18-80 years
Brief Summary
A variety of studies demonstrate that ocular blood flow is altered in glaucoma. Various animal and human studies have shown an increase in retinal and optic nerve head blood flow in response to diffus...
Eligibility Criteria
Inclusion
- Men and women aged between 20 and 80 years.
- Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant.
- Inclusion criteria of patients are open angle glaucoma.
- Men and women will be included in equal parts. A pregnancy test will be performed at screening.
- Ametropia of less than 3 diopters and anisometropia of less than 1 diopter.
Exclusion
- Treatment with vasoactive drugs.
- Presence of intraocular pathology other than open angle glaucoma.
- Presence of ocular hypertension or PEX (pseudoexfoliation) glaucoma
- History or family history of epilepsy.
- Pregnancy.
- Diabetes mellitus.
Key Trial Info
Start Date :
October 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2012
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00811694
Start Date
October 1 2006
End Date
May 1 2012
Last Update
November 21 2014
Active Locations (1)
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1
Department of Clinical Pharmacology, Meical University of Vienna, Austria
Vienna, Austria, 1090