Status:

COMPLETED

Phase 1B Study of RiVax, a Vaccine to Prevent the Toxic Effects of Ricin

Lead Sponsor:

University of Texas Southwestern Medical Center

Conditions:

Healthy

Eligibility:

All Genders

18-31 years

Phase:

PHASE1

Brief Summary

Dose escalation study: 3 dose groups. 5 patients in each dose group, then 15 more patients in "best" group. 3 vaccinations in volunteers, at 0 6 and 16 weeks.

Detailed Description

Final report was submitted to Dr. Karen Russell at FDA, Rockville on September 26, 2012.

Eligibility Criteria

Inclusion

  • healthy volunteers aged 18-31, m or f

Exclusion

  • immunodeficiency
  • pregnant
  • chronic disease
  • parental IgG
  • abnormal labs
  • drug use
  • hiv
  • hep c
  • hep b

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2012

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00812071

Start Date

March 1 2008

End Date

May 1 2012

Last Update

August 20 2013

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hampton Roads Center For Clinical Research

Chesapeake, Virginia, United States, 23320