Status:
COMPLETED
Effects of Continuous Positive Airway Pressure (CPAP) in Patients With Resistant Hypertension and Obstructive Sleep Apnea (OSA)
Lead Sponsor:
University of Sao Paulo
Conditions:
Obstructive Sleep Apnea
Refractory Hypertension
Eligibility:
All Genders
30-65 years
Phase:
PHASE3
Brief Summary
Obstructive sleep apnea (OSA) is an important cause of refractory hypertension but the impact of treatment with continuous positive airway pressure (CPAP) is not completely understood. The aim of this...
Detailed Description
Study design Interventional, open-label, randomized. Patients selection Fifty refractory hypertensive patients with moderate-to-severe OSA, aged between 30 to 65 years old will be recruited from the...
Eligibility Criteria
Inclusion
- Refractory hypertensive patients with moderate-to-severe OSA, aged between 30 to 65 years old.
Exclusion
- Aortic, heart and valve diseases
- Renal failure
- Other identifiable causes of hypertension, no adherence, use of cocaine, amphetamines, other illicit drugs, sympathomimetics (decongestants, anorectics), oral contraceptive hormones, nonsteroidal anti-inflammatory drugs.
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00812695
Start Date
October 1 2008
End Date
March 1 2011
Last Update
November 23 2011
Active Locations (1)
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1
Heart Institute (InCor)
São Paulo, São Paulo, Brazil, 05403-904