Status:
COMPLETED
Effect of β-alanine Supplementation on Muscle Carnosine
Lead Sponsor:
Société des Produits Nestlé (SPN)
Collaborating Sponsors:
University of Bern
Insel Gruppe AG, University Hospital Bern
Conditions:
Healthy
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
Carnosine is a natural acid buffering substance of muscle. The primary objective of this study is to test whether a nutritional supplement of beta-alanine enhances carnosine content in muscle.
Detailed Description
Volunteers will be randomized to receiving 3 nutritional supplements. Two supplements contain beta-alanine at different doses, the third supplement is a placebo.
Eligibility Criteria
Inclusion
- Stable health as evaluated by medical evaluation
- Body mass index higher than 18 kg/m2
- Body mass index lower than 25 kg/m2, unless body fat is less than 20%
Exclusion
- intolerance to β-alanine,
- allergy to soy, fish and crustacean
- participation in another intervention study
- consumer of dietary supplement susceptible to contain beta-alanine
- determined to have very high baseline muscle carnosine concentration
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00813553
Start Date
December 1 2008
End Date
October 1 2009
Last Update
April 25 2012
Active Locations (1)
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1
University and Inselspital
Bern, Canton of Bern, Switzerland, 3010