Status:

UNKNOWN

CYP2D6 Genotyping by AmpliChipTM CYP450 for Tamoxifen-Treated Breast Cancer Patients

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

The aim of the study is to examine whether tamoxifen-treated Israeli breast cancer patients who are CYP2D6 poor metabolizers (CYP2D6\*4/\*4 genotype) are at higher cancer relapse risk during 2.5-5-yea...

Detailed Description

Tamoxifen, the first-line drug for preventing breast cancer relapse, is typically prescribed for a 5-year follow-up period after diagnosis and primary treatment of estrogen receptor-positive breast ca...

Eligibility Criteria

Inclusion

  • Female
  • Age \> 18
  • Treated with Tamoxifen following diagnosis of breast cancer

Exclusion

  • None

Key Trial Info

Start Date :

December 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT00815555

Start Date

December 1 2008

Last Update

December 30 2008

Active Locations (1)

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Clinical Pharmacology Unit - Assaf Harofeh Medical Center

Ẕerifin, Israel, 70300