Status:
UNKNOWN
Pharmacogenomic Study to Predict Antidepressant Responsiveness in Depressed Patients
Lead Sponsor:
Samsung Medical Center
Conditions:
Depression
Adverse Reaction to Drug
Eligibility:
All Genders
19-89 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether pharmacogenomic study predict antidepressant responsiveness in advance before the appearance of the drug effects until 4\~6 weeks after drug administr...
Detailed Description
The purpose of this study is 1. to determine whether genomic effects on antidepressant response differed by class of drug, 2. whether genomic differences between drug responders and nonresponders pre...
Eligibility Criteria
Inclusion
- Eligible patients were enrolled in the clinical trials program of hte Samsung Medical Center Geropsychiatry and Affective Disorder Clinics(Seoul, Korea). They received a semistructured diagnostic interview, the Samsung Psychiatric Evaluation Schedule. The affective disorder section of the Samsung Psychiatric Evaluation Schedule uses the Korean version of the structured clinical interview for the diagnostic and statistical manual of mental disorders, Fourth edition.
- interview with one more patient's family member for objective diagnosis and final diagnosis decision by agreements of two more psychiatric physicians
Exclusion
- received psychotropic medication within 2 weeks of the study or fluoxetine within 4 weeks
- potential study participants for pregnancy, significant medical conditions, abnormal laboratory baseline values, unstable psychiatric features(eg.suicidal), history of alcohol of drug dependence, seizures, head trauma with loss of consciousness, neurological illness, or concomitant Axis I psychiatric disorder.
Key Trial Info
Start Date :
February 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2018
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT00817375
Start Date
February 1 2003
End Date
December 1 2018
Last Update
December 31 2015
Active Locations (1)
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1
Samsung Medical Center
Kangnam, Seoul, South Korea, 135-710